I'm also on Vista (it came with my new laptop) and honestly, I went with it kicking and screaming. I'd been on XP for so long it felt like pulling teeth to switch. I also resisted using Windows Mail (as opposed to Outlook Express which is no longer available) and complained for at least a week that it 'wasn't working properly'
It's really fine, and not all that buggy, actually. Now that I'm used to it I don't even notice a difference and actually like Windows Mail just fine.
I navigate my files and folders much easier as well, there are cool little ins and outs on Vista that just make it faster.
When you consider how BIG the software package really is it's understandable that these things are released with the knowledge that there will be bugs and the assumption that patches are coming. There's a big patch meant to come out very soon (I've read).
Note: I'm *not* linked up with any virtual PC programs, just our internal network (we use an external, in-house program for client collaboration and storage of files, etc.)